STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0C3F456Uncharacterized protein. (729 aa)    
Predicted Functional Partners:
A0A0C3G600
Uncharacterized protein.
   
 0.910
A0A0C3FUZ3
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.891
A0A0C3EZC4
DUF1767 domain-containing protein.
    
 0.880
A0A0C3BGB8
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.877
A0A0C3G7Z3
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.873
A0A0C3FNV7
RECA_2 domain-containing protein.
   
 0.855
A0A0C3BT01
Uncharacterized protein.
  
 0.835
A0A0C3FJE8
Uncharacterized protein.
   
 0.832
A0A0C3C422
RECA_2 domain-containing protein.
   
 0.824
A0A0C3F5Z4
Rad51 domain-containing protein.
   
 0.824
Your Current Organism:
Piloderma croceum
NCBI taxonomy Id: 765440
Other names: P. croceum F 1598, Piloderma croceum F 1598
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.