SDX19601.1 protein (Acidimangrovimonas indica)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

SDX19601.1

8-oxo-dGTP pyrophosphatase MutT, NUDIX family. (184 aa)

Predicted Functional Partners:

SDW64640.1

0.988

SDW87224.1

0.923

SDX23317.1

0.923

SDX47910.1

0.923

SDW93564.1

0.861

SDX48092.1

0.859

SDX52817.1

0.858

SDX17844.1

0.818

SDW96921.1

0.778

SDW51127.1

0.773

Your Current Organism:

Acidimangrovimonas indica

NCBI taxonomy Id: 765699
Other names: A. indica, Acidimangrovimonas indica (Jiang et al. 2014) Ren et al. 2019, CGMCC 1.10859, DSM 24802, Defluviimonas indica, Defluviimonas indica Jiang et al. 2014, JCM 17871, MCCC 1A01802, Rhodobacter sp. 20V17, strain 20V17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDW51127.1	SDW87224.1	SAMN05444006_104124	SAMN05444006_107167	RNAse PH.	Superfamily II DNA and RNA helicase.	0.830
SDW51127.1	SDW93564.1	SAMN05444006_104124	SAMN05444006_10868	RNAse PH.	RNAse III.	0.402
SDW51127.1	SDX19601.1	SAMN05444006_104124	SAMN05444006_111118	RNAse PH.	8-oxo-dGTP pyrophosphatase MutT, NUDIX family.	0.773
SDW51127.1	SDX23317.1	SAMN05444006_104124	SAMN05444006_11249	RNAse PH.	ATP-dependent RNA helicase DeaD.	0.807
SDW51127.1	SDX47910.1	SAMN05444006_104124	SAMN05444006_11750	RNAse PH.	ATP-dependent RNA helicase RhlE.	0.830
SDW51127.1	SDX48092.1	SAMN05444006_104124	SAMN05444006_11756	RNAse PH.	RNAse R.	0.997
SDW51127.1	SDX52817.1	SAMN05444006_104124	SAMN05444006_11920	RNAse PH.	ATP-dependent helicase HrpB.	0.943
SDW64640.1	SDW87224.1	SAMN05444006_105204	SAMN05444006_107167	yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region.	Superfamily II DNA and RNA helicase.	0.988
SDW64640.1	SDX19601.1	SAMN05444006_105204	SAMN05444006_111118	yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region.	8-oxo-dGTP pyrophosphatase MutT, NUDIX family.	0.988
SDW64640.1	SDX23317.1	SAMN05444006_105204	SAMN05444006_11249	yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region.	ATP-dependent RNA helicase DeaD.	0.988
SDW64640.1	SDX47910.1	SAMN05444006_105204	SAMN05444006_11750	yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region.	ATP-dependent RNA helicase RhlE.	0.988
SDW87224.1	SDW51127.1	SAMN05444006_107167	SAMN05444006_104124	Superfamily II DNA and RNA helicase.	RNAse PH.	0.830
SDW87224.1	SDW64640.1	SAMN05444006_107167	SAMN05444006_105204	Superfamily II DNA and RNA helicase.	yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region.	0.988
SDW87224.1	SDW93564.1	SAMN05444006_107167	SAMN05444006_10868	Superfamily II DNA and RNA helicase.	RNAse III.	0.950
SDW87224.1	SDX19601.1	SAMN05444006_107167	SAMN05444006_111118	Superfamily II DNA and RNA helicase.	8-oxo-dGTP pyrophosphatase MutT, NUDIX family.	0.923
SDW87224.1	SDX47910.1	SAMN05444006_107167	SAMN05444006_11750	Superfamily II DNA and RNA helicase.	ATP-dependent RNA helicase RhlE.	0.679
SDW87224.1	SDX48092.1	SAMN05444006_107167	SAMN05444006_11756	Superfamily II DNA and RNA helicase.	RNAse R.	0.645
SDW87224.1	SDX52817.1	SAMN05444006_107167	SAMN05444006_11920	Superfamily II DNA and RNA helicase.	ATP-dependent helicase HrpB.	0.986
SDW93564.1	SDW51127.1	SAMN05444006_10868	SAMN05444006_104124	RNAse III.	RNAse PH.	0.402
SDW93564.1	SDW87224.1	SAMN05444006_10868	SAMN05444006_107167	RNAse III.	Superfamily II DNA and RNA helicase.	0.950

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

49

average node degree:

8.91

avg. local clustering coefficient:

0.915

expected number of edges:

32

PPI enrichment p-value:

0.00331

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006281

DNA repair

7 of 68

1.75

3.08

7.38e-09

GO:0006259

DNA metabolic process

9 of 215

1.36

2.1

7.38e-09

GO:0009432

SOS response

3 of 15

2.04

1.81

0.00025

GO:0006310

DNA recombination

4 of 71

1.49

1.39

0.00042

GO:0019363

Pyridine nucleotide biosynthetic process

2 of 8

2.14

1.17

0.0062

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003684

Damaged DNA binding

3 of 9

2.26

1.9

0.00024

GO:0140097

Catalytic activity, acting on DNA

6 of 104

1.5

1.84

9.90e-06

GO:0140640

Catalytic activity, acting on a nucleic acid

7 of 239

1.2

1.34

1.78e-05

GO:0140664

ATP-dependent DNA damage sensor activity

2 of 6

2.26

1.26

0.0045

GO:0008094

ATP-dependent activity, acting on DNA

3 of 32

1.71

1.24

0.0026

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1632

DNA repair, and DNA damage sensor activity

8 of 29

2.18

5.57

1.79e-13

CL:1634

Mixed, incl. DNA damage sensor activity, and RecQ zinc-binding

3 of 16

2.01

1.41

0.0018

CL:1652

Mixed, incl. RecQ zinc-binding, and UvrD/REP helicase N-terminal domain

2 of 7

2.19

0.8

0.0332

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03440

Homologous recombination

4 of 40

1.74

1.8

9.99e-05

map03420

Nucleotide excision repair

3 of 26

1.8

1.45

0.0010

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0234

DNA repair

6 of 26

2.1

4.03

1.32e-09

KW-0742

SOS response

3 of 6

2.44

2.42

2.68e-05

KW-0235

DNA replication

2 of 13

1.92

1.01

0.0111

KW-0238

DNA-binding

5 of 199

1.14

0.99

0.00088

KW-0378

Hydrolase

5 of 269

1.01

0.78

0.0029

(more ...)

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