STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A178DRK2Clavaminate synthase-like protein. (375 aa)    
Predicted Functional Partners:
A0A178E100
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.
   
  
 0.907
A0A178EMX8
CENP-T_C domain-containing protein.
   
 0.702
A0A178DKZ9
dUTP diphosphatase.
   
 0.691
A0A178ELH9
P-loop containing nucleoside triphosphate hydrolase protein.
    
 0.655
A0A178E5A2
DNA repair endonuclease XPF.
    
 0.624
A0A178E8K8
Allantoicase.
   
  
 0.605
A0A178EEK4
Ribonuclease P protein subunit.
   
 0.532
A0A178E3Q5
SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...]
    
 0.531
A0A178E8J5
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
  0.530
A0A178EH59
Uncharacterized protein.
   
 0.530
Your Current Organism:
Pyrenochaeta sp. DS3sAY3a
NCBI taxonomy Id: 765867
Other names: P. sp. DS3sAY3a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.