STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A178DRL22-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (455 aa)    
Predicted Functional Partners:
A0A178E1C9
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.994
A0A178E2V6
Thiamin diphosphate-binding protein.
 0.993
A0A178DNV0
Thiamin diphosphate-binding protein.
 0.992
A0A178E1I7
Thiamin diphosphate-binding protein.
 0.992
A0A178DSZ6
Thiamin diphosphate-binding protein.
 0.991
A0A178E2X4
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.897
A0A178E577
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.897
A0A178DTC3
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.896
A0A178E328
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.896
A0A178DV54
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.895
Your Current Organism:
Pyrenochaeta sp. DS3sAY3a
NCBI taxonomy Id: 765867
Other names: P. sp. DS3sAY3a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.