Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A178AB40Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (550 aa)    
Predicted Functional Partners:
A0A178AK01
Histidine biosynthesis trifunctional protein.
 
 0.999
A0A178AXM4
IGPD-domain-containing protein.
 
 
 0.991
A0A178AEW7
Histidinol-phosphate aminotransferase.
 
 
 0.983
A0A178BCR8
HisG-domain-containing protein.
 
 
 0.983
A0A178AZH6
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
 
 
 0.979
A0A178AGR6
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.941
A0A178APB6
HET-domain-containing protein.
  
 
 0.938
A0A178AR83
HET-domain-containing protein.
  
 
 0.938
A0A178AVJ8
Helicase ATP-binding domain-containing protein.
  
 
 0.924
A0A178B1K0
Uncharacterized protein.
  
 
 0.924
Your Current Organism:
Stagonospora sp. SRC1lsM3a
NCBI taxonomy Id: 765868
Other names: S. sp. SRC1lsM3a
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