| node1 | node2 | node1 annotation | node2 annotation | score |
| A0A178AB40 | A0A178AEW7 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Histidinol-phosphate aminotransferase. | 0.983 |
| A0A178AB40 | A0A178AGR6 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.941 |
| A0A178AB40 | A0A178AK01 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Histidine biosynthesis trifunctional protein. | 0.999 |
| A0A178AB40 | A0A178APB6 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | HET-domain-containing protein. | 0.938 |
| A0A178AB40 | A0A178AR83 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | HET-domain-containing protein. | 0.938 |
| A0A178AB40 | A0A178AVJ8 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Helicase ATP-binding domain-containing protein. | 0.924 |
| A0A178AB40 | A0A178AXM4 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | IGPD-domain-containing protein. | 0.991 |
| A0A178AB40 | A0A178AZH6 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.979 |
| A0A178AB40 | A0A178B1K0 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Uncharacterized protein. | 0.924 |
| A0A178AB40 | A0A178BCR8 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | HisG-domain-containing protein. | 0.983 |
| A0A178AEW7 | A0A178AB40 | Histidinol-phosphate aminotransferase. | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 0.983 |
| A0A178AEW7 | A0A178AK01 | Histidinol-phosphate aminotransferase. | Histidine biosynthesis trifunctional protein. | 0.999 |
| A0A178AEW7 | A0A178APB6 | Histidinol-phosphate aminotransferase. | HET-domain-containing protein. | 0.855 |
| A0A178AEW7 | A0A178AR83 | Histidinol-phosphate aminotransferase. | HET-domain-containing protein. | 0.855 |
| A0A178AEW7 | A0A178AVJ8 | Histidinol-phosphate aminotransferase. | Helicase ATP-binding domain-containing protein. | 0.937 |
| A0A178AEW7 | A0A178AXM4 | Histidinol-phosphate aminotransferase. | IGPD-domain-containing protein. | 0.999 |
| A0A178AEW7 | A0A178AZH6 | Histidinol-phosphate aminotransferase. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.885 |
| A0A178AEW7 | A0A178B1K0 | Histidinol-phosphate aminotransferase. | Uncharacterized protein. | 0.937 |
| A0A178AEW7 | A0A178BCR8 | Histidinol-phosphate aminotransferase. | HisG-domain-containing protein. | 0.967 |
| A0A178AGR6 | A0A178AB40 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 0.941 |