Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A178ADG8Isocitrate/isopropylmalate dehydrogenase. (357 aa)    
Predicted Functional Partners:
A0A178AWK8
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
 
 0.991
A0A178BAV5
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
0.981
A0A178AYM1
Saccharopine dehydrogenase.
   
 
 0.946
A0A178AG21
2-oxoglutarate dehydrogenase-like protein E1 component.
   
 0.893
A0A178BBB0
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
   0.874
A0A178AQ64
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.873
A0A178AE47
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.871
A0A178B5P1
Homocitrate synthase-like protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 0.868
A0A178AY81
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.
   
 
 0.861
A0A178AKB0
Argininosuccinate lyase.
  
 
 0.855
Your Current Organism:
Stagonospora sp. SRC1lsM3a
NCBI taxonomy Id: 765868
Other names: S. sp. SRC1lsM3a
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