Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A178AF82Methylisocitrate lyase-like protein. (313 aa)    
Predicted Functional Partners:
A0A178AKJ0
Malate synthase; Belongs to the malate synthase family.
   
 0.907
A0A178AK96
Acetyl-coenzyme A synthetase.
  
 
 0.825
A0A178AZF6
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.802
A0A178B2W0
Succinyl-CoA ligase-like protein subunit alpha.
    
 0.802
A0A178B3X3
2-isopropylmalate synthase.
  
 
  0.775
A0A178B5P1
Homocitrate synthase-like protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
  0.775
A0A178BCI8
Acetyl-CoA acetyltransferase IB; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
  0.774
A0A178AUE1
Uncharacterized protein.
    
 0.770
A0A178B031
AcetylCoA_hyd_C domain-containing protein.
  
 
 0.767
A0A178ATV8
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
 0.764
Your Current Organism:
Stagonospora sp. SRC1lsM3a
NCBI taxonomy Id: 765868
Other names: S. sp. SRC1lsM3a
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