| node1 | node2 | node1 annotation | node2 annotation | score |
| A0A178AB40 | A0A178ABK1 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Adenine phosphoribosyltransferase. | 0.894 |
| A0A178AB40 | A0A178AGR6 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.941 |
| A0A178AB40 | A0A178AKB4 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Amidophosphoribosyltransferase. | 0.442 |
| A0A178AB40 | A0A178AP99 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. | 0.588 |
| A0A178AB40 | A0A178AYA8 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Phosphoribosylamine-glycine ligase. | 0.656 |
| A0A178AB40 | A0A178AYB5 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | AICARFT/IMPCHase bienzyme. | 0.911 |
| A0A178AB40 | A0A178B854 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | SAICAR synthetase. | 0.410 |
| A0A178ABK1 | A0A178AB40 | Adenine phosphoribosyltransferase. | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 0.894 |
| A0A178ABK1 | A0A178AED5 | Adenine phosphoribosyltransferase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.872 |
| A0A178ABK1 | A0A178AGR6 | Adenine phosphoribosyltransferase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.976 |
| A0A178ABK1 | A0A178AKB4 | Adenine phosphoribosyltransferase. | Amidophosphoribosyltransferase. | 0.564 |
| A0A178ABK1 | A0A178AP99 | Adenine phosphoribosyltransferase. | Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. | 0.517 |
| A0A178ABK1 | A0A178AYB5 | Adenine phosphoribosyltransferase. | AICARFT/IMPCHase bienzyme. | 0.969 |
| A0A178ABK1 | A0A178B8K5 | Adenine phosphoribosyltransferase. | Ribokinase-like protein. | 0.994 |
| A0A178ABK1 | A0A178BC65 | Adenine phosphoribosyltransferase. | AMP deaminase. | 0.965 |
| A0A178AED5 | A0A178ABK1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenine phosphoribosyltransferase. | 0.872 |
| A0A178AED5 | A0A178AGR6 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.990 |
| A0A178AED5 | A0A178AKB4 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Amidophosphoribosyltransferase. | 0.950 |
| A0A178AED5 | A0A178AP99 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. | 0.949 |
| A0A178AED5 | A0A178AYA8 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Phosphoribosylamine-glycine ligase. | 0.925 |