Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A178AI79DNA replication initiation factor-like protein Cdc45. (853 aa)    
Predicted Functional Partners:
A0A178ADH8
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
   
 0.999
A0A178AG19
DNA replication complex GINS protein PSF3.
   
 0.999
A0A178AN11
SLD3 domain-containing protein.
    
 0.999
A0A178AQ83
DNA replication complex GINS protein PSF1.
   
 0.999
A0A178ATX8
DNA helicase; Belongs to the MCM family.
   
 0.999
A0A178AV49
DNA helicase; Belongs to the MCM family.
   
 0.999
A0A178AV59
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 0.999
A0A178B1U7
DNA helicase; Belongs to the MCM family.
   
 0.999
A0A178B3T1
DNA helicase; Belongs to the MCM family.
   
 0.999
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.999
Your Current Organism:
Stagonospora sp. SRC1lsM3a
NCBI taxonomy Id: 765868
Other names: S. sp. SRC1lsM3a
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