| node1 | node2 | node1 annotation | node2 annotation | score |
| A0A178A9F8 | A0A178AB62 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.874 |
| A0A178A9F8 | A0A178ADH5 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Spermine synthase; Belongs to the spermidine/spermine synthase family. | 0.933 |
| A0A178A9F8 | A0A178AF07 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.921 |
| A0A178A9F8 | A0A178AJJ8 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.629 |
| A0A178A9F8 | A0A178AKZ9 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family. | 0.715 |
| A0A178A9F8 | A0A178AL19 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.927 |
| A0A178A9F8 | A0A178ALG7 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | Tryptophan synthase. | 0.854 |
| A0A178A9F8 | A0A178AMJ3 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 1-aminocyclopropane-1-carboxylate synthase. | 0.801 |
| A0A178A9F8 | A0A178B403 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | S-adenosylmethionine decarboxylase. | 0.956 |
| A0A178A9F8 | A0A178B414 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | NAD(P)-binding protein. | 0.992 |
| A0A178AB62 | A0A178A9F8 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.874 |
| A0A178AB62 | A0A178AL19 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.953 |
| A0A178AB62 | A0A178AMJ3 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 1-aminocyclopropane-1-carboxylate synthase. | 0.729 |
| A0A178AB62 | A0A178B403 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine decarboxylase. | 0.874 |
| A0A178AB62 | A0A178B414 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | NAD(P)-binding protein. | 0.896 |
| A0A178ADH5 | A0A178A9F8 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.933 |
| A0A178ADH5 | A0A178AF07 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.667 |
| A0A178ADH5 | A0A178AJJ8 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.964 |
| A0A178ADH5 | A0A178AKZ9 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | Bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family. | 0.755 |
| A0A178ADH5 | A0A178AL19 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.682 |