| node1 | node2 | node1 annotation | node2 annotation | score |
| A0A178A7C3 | A0A178AD74 | Uncharacterized protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.895 |
| A0A178A7C3 | A0A178AJJ8 | Uncharacterized protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.670 |
| A0A178A7C3 | A0A178AN28 | Uncharacterized protein. | Xanthine dehydrogenase. | 0.874 |
| A0A178A7C3 | A0A178APL4 | Uncharacterized protein. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.797 |
| A0A178A7C3 | A0A178APN9 | Uncharacterized protein. | Metallo-dependent hydrolase. | 0.787 |
| A0A178A7C3 | A0A178ASX9 | Uncharacterized protein. | Hypoxanthine guanine phosphoribosyltransferase. | 0.710 |
| A0A178AB62 | A0A178AL19 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.953 |
| A0A178AB62 | A0A178APL4 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.652 |
| A0A178AB62 | A0A178APN9 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Metallo-dependent hydrolase. | 0.652 |
| A0A178AD74 | A0A178A7C3 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Uncharacterized protein. | 0.895 |
| A0A178AD74 | A0A178ADH5 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Spermine synthase; Belongs to the spermidine/spermine synthase family. | 0.817 |
| A0A178AD74 | A0A178AN28 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Xanthine dehydrogenase. | 0.895 |
| A0A178AD74 | A0A178APL4 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.766 |
| A0A178AD74 | A0A178APN9 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Metallo-dependent hydrolase. | 0.799 |
| A0A178AD74 | A0A178ASX9 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Hypoxanthine guanine phosphoribosyltransferase. | 0.825 |
| A0A178ADH5 | A0A178AD74 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.817 |
| A0A178ADH5 | A0A178AJJ8 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.964 |
| A0A178ADH5 | A0A178AL19 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.682 |
| A0A178ADH5 | A0A178APL4 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.651 |
| A0A178ADH5 | A0A178APN9 | Spermine synthase; Belongs to the spermidine/spermine synthase family. | Metallo-dependent hydrolase. | 0.651 |