STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHF02505.1Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)    
Predicted Functional Partners:
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.978
AHF02480.1
Hydrogenase formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family.
 
  
 0.964
AHF02481.1
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.957
AHF05255.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.953
AHF02479.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.879
AHF04221.1
Carbamoyltransferase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.861
AHF03554.1
Hydrogenase assembly protein HypC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.820
AHF04513.1
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.798
AHF03551.1
Ni/Fe hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.677
AHF03341.1
NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.633
Your Current Organism:
Marichromatium purpuratum
NCBI taxonomy Id: 765910
Other names: M. purpuratum 984, Marichromatium purpuratum 984, Marichromatium purpuratum str. 984, Marichromatium purpuratum strain 984
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.