Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AHF03014.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (124 aa)    
Predicted Functional Partners:
AHF04409.1
Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.817
AHF04106.1
Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.808
groEL
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.753
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
     0.640
AHF03562.1
Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.621
AHF02844.1
Glutathione amide-dependent peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.606
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
  
 
 0.594
AHF03015.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.592
AHF05266.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.515
groS
Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 
 
 0.466
Your Current Organism:
Marichromatium purpuratum
NCBI taxonomy Id: 765910
Other names: M. purpuratum 984, Marichromatium purpuratum 984, Marichromatium purpuratum str. 984, Marichromatium purpuratum strain 984
Server load: low (8%) [HD]