node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGA90291.1 | AGA90292.1 | Thimo_1506 | Thimo_1507 | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | PFAM: Protein of unknown function (DUF3050). | 0.590 |
AGA90291.1 | aroE | Thimo_1506 | Thimo_0134 | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.571 |
AGA90291.1 | infA | Thimo_1506 | Thimo_2091 | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.497 |
AGA90291.1 | nadD | Thimo_1506 | Thimo_1080 | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.841 |
AGA90291.1 | rsfS | Thimo_1506 | Thimo_1079 | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.585 |
AGA90291.1 | topA | Thimo_1506 | Thimo_1256 | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | DNA topoisomerase I, bacterial; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removi [...] | 0.488 |
AGA90292.1 | AGA90291.1 | Thimo_1507 | Thimo_1506 | PFAM: Protein of unknown function (DUF3050). | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | 0.590 |
aroE | AGA90291.1 | Thimo_0134 | Thimo_1506 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | 0.571 |
aroE | nadD | Thimo_0134 | Thimo_1080 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.822 |
aroE | rsfS | Thimo_0134 | Thimo_1079 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.412 |
aroE | topA | Thimo_0134 | Thimo_1256 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | DNA topoisomerase I, bacterial; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removi [...] | 0.532 |
infA | AGA90291.1 | Thimo_2091 | Thimo_1506 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | 0.497 |
nadD | AGA90291.1 | Thimo_1080 | Thimo_1506 | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | 0.841 |
nadD | aroE | Thimo_1080 | Thimo_0134 | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.822 |
nadD | rsfS | Thimo_1080 | Thimo_1079 | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.992 |
rsfS | AGA90291.1 | Thimo_1079 | Thimo_1506 | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | 0.585 |
rsfS | aroE | Thimo_1079 | Thimo_0134 | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.412 |
rsfS | nadD | Thimo_1079 | Thimo_1080 | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | Nicotinate/nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.992 |
topA | AGA90291.1 | Thimo_1256 | Thimo_1506 | DNA topoisomerase I, bacterial; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removi [...] | Putative RNA-binding protein containing KH domain, possibly ribosomal protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: putative RNA-binding protein, YhbY family. | 0.488 |
topA | aroE | Thimo_1256 | Thimo_0134 | DNA topoisomerase I, bacterial; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removi [...] | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.532 |