Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGA90750.1Type I restriction-modification system methyltransferase subunit; PFAM: N-6 DNA Methylase; HsdM N-terminal domain. (482 aa)    
Predicted Functional Partners:
AGA90749.1
PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit; EcoEI R protein C-terminal.
 
 
 0.988
AGA90755.1
PFAM: Type I restriction modification DNA specificity domain.
 
 0.988
AGA92117.1
PFAM: Type I restriction modification DNA specificity domain; manually curated.
 
 
 0.971
AGA92125.1
PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit.
  
  
 0.838
AGA90748.1
Hypothetical protein.
       0.615
AGA90751.1
Hypothetical protein.
       0.517
AGA90752.1
Hypothetical protein.
       0.517
AGA89737.1
Hypothetical protein.
  
  
 0.430
AGA90747.1
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.423
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
   0.415
Your Current Organism:
Thioflavicoccus mobilis
NCBI taxonomy Id: 765912
Other names: T. mobilis 8321, Thioflavicoccus mobilis 8321, Thioflavicoccus mobilis ATCC 700959, Thioflavicoccus mobilis str. 8321, Thioflavicoccus mobilis strain 8321
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