STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGV33666.1TIGRFAM: HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: alv:Alvin_1976 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region. (448 aa)    
Predicted Functional Partners:
EGV28609.1
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
   
 0.883
EGV28212.1
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
   
 0.883
EGV32420.1
Serine/threonine protein kinase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; Serine/threonine-protein kinase-like domain; GAF; KEGG: ana:alr0354 serine/threonine kinase protein; SMART: Diguanylate cyclase, predicted; Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; GAF.
    
 0.879
EGV31018.1
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; MCP methyltransferase, CheR-type; PAS fold-4; KEGG: alv:Alvin_1169 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; SMART: MCP methyltransferase, CheR-type; PAS.
   
   0.825
EGV29130.1
KEGG: cja:CJA_0326 diguanylate cyclase (GGDEF) domain protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted.
 
 
 0.773
EGV27566.1
PFAM: CHASE2; KEGG: nhl:Nhal_3548 CHASE2 domain protein.
    
  0.770
EGV31340.1
PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: alv:Alvin_1172 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
   
   0.768
EGV30779.1
TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: alv:Alvin_0264 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
   
   0.768
EGV31350.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; CHASE; Signal transduction response regulator, receiver region; KEGG: alv:Alvin_2874 multi-sensor hybrid histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; PAC motif; Signal transduction response regulator, receiver region.
 
  
 0.760
EGV32465.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.716
Your Current Organism:
Thiorhodococcus drewsii
NCBI taxonomy Id: 765913
Other names: T. drewsii AZ1, Thiorhodococcus drewsii AZ1, Thiorhodococcus drewsii DSM 15006, Thiorhodococcus drewsii str. AZ1, Thiorhodococcus drewsii strain AZ1
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