STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGV33041.1PFAM: 6-pyruvoyl tetrahydropterin synthase-related; KEGG: alv:Alvin_2762 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. (364 aa)    
Predicted Functional Partners:
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.996
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.970
EGV27924.1
3-phytase; KEGG: cyt:cce_3495 phytase; PFAM: Phytase.
     
 0.916
folE
PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; TIGRFAM: GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; KEGG: nhl:Nhal_1382 GTP cyclohydrolase I.
  
 
 0.901
folE2
Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate.
    
 0.889
EGV33175.1
PFAM: NUDIX hydrolase domain; KEGG: alv:Alvin_0721 NUDIX hydrolase.
 
  
  0.882
EGV32674.1
PFAM: Radical SAM; KEGG: fal:FRAAL0840 putative radical activating enzyme.
  
 
 0.867
EGV32898.1
KEGG: alv:Alvin_1560 hypothetical protein.
    
  0.851
queF
NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
  
 0.738
EGV33850.1
KEGG: alv:Alvin_0843 cyclic nucleotide-regulated small mechanosensitive ion channel; PFAM: Mechanosensitive ion channel MscS; Cyclic nucleotide-binding; SMART: Cyclic nucleotide-binding.
    
  0.632
Your Current Organism:
Thiorhodococcus drewsii
NCBI taxonomy Id: 765913
Other names: T. drewsii AZ1, Thiorhodococcus drewsii AZ1, Thiorhodococcus drewsii DSM 15006, Thiorhodococcus drewsii str. AZ1, Thiorhodococcus drewsii strain AZ1
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