STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGV31291.1TIGRFAM: Histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; KEGG: alv:Alvin_3004 histidinol-phosphate phosphatase family protein. (195 aa)    
Predicted Functional Partners:
EGV31207.1
PFAM: Sugar isomerase (SIS); KEGG: alv:Alvin_3036 sugar isomerase (SIS).
 
 0.998
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family.
  
 
 0.997
EGV33439.1
PFAM: ATP dependent DNA ligase, central; KEGG: alv:Alvin_0262 ATP dependent DNA ligase.
 
 
 0.983
hldE
Bifunctional protein hldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
  
 0.978
EGV27981.1
PFAM: Nucleotidyl transferase; Cystathionine beta-synthase, core; KEGG: gka:GK3121 nucleoside-diphosphate-sugar pyrophosphorylase.
 
 0.960
EGV28974.1
PFAM: Glycosyl transferase, family 9; KEGG: alv:Alvin_2608 lipopolysaccharide heptosyltransferase II.
  
 0.936
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.921
EGV27994.1
PFAM: Glutamine amidotransferase class-I, C-terminal; KEGG: ure:UREG_05681 imidazole glycerol phosphate synthase hisHF.
  
 
 0.893
EGV30025.1
TIGRFAM: UDP-glucose 4-epimerase; KEGG: alv:Alvin_1650 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
    
 0.890
EGV28121.1
TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: alv:Alvin_0920 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase.
  
 
  0.855
Your Current Organism:
Thiorhodococcus drewsii
NCBI taxonomy Id: 765913
Other names: T. drewsii AZ1, Thiorhodococcus drewsii AZ1, Thiorhodococcus drewsii DSM 15006, Thiorhodococcus drewsii str. AZ1, Thiorhodococcus drewsii strain AZ1
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