STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGV30577.1PFAM: Bacterial lipid A biosynthesis acyltransferase; KEGG: alv:Alvin_0867 lipid A biosynthesis acyltransferase. (345 aa)    
Predicted Functional Partners:
EGV28340.1
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.954
EGV30035.1
PFAM: Bacterial lipid A biosynthesis acyltransferase; KEGG: alv:Alvin_1329 lipid A biosynthesis acyltransferase.
  
  
 
0.899
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 
 0.865
EGV28974.1
PFAM: Glycosyl transferase, family 9; KEGG: alv:Alvin_2608 lipopolysaccharide heptosyltransferase II.
 
  
 0.813
lpxB
Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.793
lpxD-2
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.745
EGV29907.1
PFAM: Glycosyl transferase, family 39; KEGG: alv:Alvin_1542 glycosyl transferase family 39.
 
  
 0.744
lpxC
UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.704
EGV30990.1
KpsF/GutQ family protein; SMART: Cystathionine beta-synthase, core; TIGRFAM: KpsF/GutQ; KEGG: alv:Alvin_2842 KpsF/GutQ family protein; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core.
 
   
 0.675
EGV28841.1
TIGRFAM: Amino acid adenylation; KEGG: rso:RS05860 peptide synthetase protein; PFAM: Beta-ketoacyl synthase, N-terminal; AMP-dependent synthetase/ligase; Phosphopantetheine-binding; Beta-ketoacyl synthase, C-terminal; Acyl transferase; Aminotransferase class-III; Condensation domain.
     
 0.643
Your Current Organism:
Thiorhodococcus drewsii
NCBI taxonomy Id: 765913
Other names: T. drewsii AZ1, Thiorhodococcus drewsii AZ1, Thiorhodococcus drewsii DSM 15006, Thiorhodococcus drewsii str. AZ1, Thiorhodococcus drewsii strain AZ1
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