STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGV27696.1KEGG: app:CAP2UW1_2768 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Cystathionine beta-synthase, core; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Cystathionine beta-synthase, core; GAF; Signal transduction response regulator, receiver region. (1100 aa)    
Predicted Functional Partners:
EGV33591.1
KEGG: alv:Alvin_2619 response regulator receiver protein; PFAM: Sporulation stage II, protein E C-terminal; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; Protein phosphatase 2C-related.
  
 0.999
EGV33592.1
KEGG: alv:Alvin_2619 response regulator receiver protein; PFAM: Sporulation stage II, protein E C-terminal; Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; SMART: Signal transduction response regulator, receiver region; Protein phosphatase 2C-related.
  
 0.999
EGV33448.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; TIGRFAM: Diguanylate cyclase, predicted; KEGG: alv:Alvin_0425 response regulator receiver modulated PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, recei [...]
 
0.999
EGV32829.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: tmz:Tmz1t_2682 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
 
 0.999
EGV32582.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; CHASE; PAS fold; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: neu:NE0049 sensory transduction histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response regulator, receiver region.
 
0.999
EGV32583.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; PAS fold-4; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: nmu:Nmul_A1556 multi-sensor hybrid histidine kinase; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; PAC motif.
 
0.999
EGV32420.1
Serine/threonine protein kinase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; Serine/threonine-protein kinase-like domain; GAF; KEGG: ana:alr0354 serine/threonine kinase protein; SMART: Diguanylate cyclase, predicted; Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; GAF.
 0.999
EGV31963.1
KEGG: nde:NIDE1046 putative hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region.
 
0.999
EGV31132.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold-3; GAF; PAS fold-4; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: app:CAP2UW1_2212 multi-sensor signal transduction histidine kinase; SMART: ATP-binding region, ATPase-like; GAF; PAC motif; PAS; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region.
 
0.999
EGV31135.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; PAS fold; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: alv:Alvin_1490 multi-sensor hybrid histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; PAS.
 
0.999
Your Current Organism:
Thiorhodococcus drewsii
NCBI taxonomy Id: 765913
Other names: T. drewsii AZ1, Thiorhodococcus drewsii AZ1, Thiorhodococcus drewsii DSM 15006, Thiorhodococcus drewsii str. AZ1, Thiorhodococcus drewsii strain AZ1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.