STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGZ50273.1PFAM: Domain of unknown function DUF559; KEGG: net:Neut_1078 hypothetical protein. (399 aa)    
Predicted Functional Partners:
EGZ45788.1
KEGG: alv:Alvin_0033 glutamate synthase (ferredoxin); PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
  
    0.834
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
  0.809
EGZ50274.1
KEGG: net:Neut_1077 hypothetical protein.
       0.695
EGZ50275.1
Sigma 54 interacting domain protein; SMART: ATPase, AAA+ type, core; KEGG: net:Neut_1076 AAA ATPase.
       0.645
EGZ49390.1
DEAD/DEAH box helicase domain protein; KEGG: eba:ebA3563 ATP-dependent RNA helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; Belongs to the DEAD box helicase family.
    
  0.614
EGZ47027.1
PFAM: Protein of unknown function DUF2081; Domain of unknown function DUF262; KEGG: dge:Dgeo_2015 hypothetical protein.
    
  0.614
EGZ40841.1
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: tgr:Tgr7_2896 5,10-methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
    
  0.606
EGZ45638.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.593
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
  0.577
EGZ50666.1
TIGRFAM: Cysteine synthase B; Cysteine synthase K/M; KEGG: tgr:Tgr7_1100 cysteine synthase B; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.562
Your Current Organism:
Thiorhodospira sibirica
NCBI taxonomy Id: 765914
Other names: T. sibirica ATCC 700588, Thiorhodospira sibirica A12, Thiorhodospira sibirica ATCC 700588, Thiorhodospira sibirica str. ATCC 700588, Thiorhodospira sibirica strain ATCC 700588
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