STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGZ47383.1PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; KEGG: mpt:Mpe_B0479 cobalamin biosynthesis protein. (246 aa)    
Predicted Functional Partners:
EGZ47381.1
precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: mca:MCA2293 precorrin-3B C17-methyltransferase/conserved domain-containing protein; PFAM: Tetrapyrrole methylase.
 
 0.999
EGZ47384.1
KEGG: pol:Bpro_2774 cobalt-factor II C20-methyltransferase / precorrin-2 C20-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; PFAM: Tetrapyrrole methylase.
 
 0.999
EGZ42838.1
Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; KEGG: pna:Pnap_2163 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase.
 
 0.999
EGZ47385.1
Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; KEGG: vap:Vapar_1020 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Tetrapyrrole methylase.
 
  
 0.997
EGZ47382.1
PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; KEGG: mgm:Mmc1_3129 cobalamin (vitamin B12) biosynthesis CbiG protein.
  
  0.994
cbiD
cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 
 0.993
EGZ42837.1
Precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; KEGG: mca:MCA2298 precorrin-8X methylmutase.
 
 
 0.976
EGZ47380.1
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 0.974
EGZ47387.1
Sirohydrochlorin ferrochelatase; KEGG: vap:Vapar_1023 cobalamin (vitamin B12) biosynthesis CbiX protein; PFAM: Cobalamin (vitamin B12) biosynthesis CbiX.
 
  
 0.973
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.943
Your Current Organism:
Thiorhodospira sibirica
NCBI taxonomy Id: 765914
Other names: T. sibirica ATCC 700588, Thiorhodospira sibirica A12, Thiorhodospira sibirica ATCC 700588, Thiorhodospira sibirica str. ATCC 700588, Thiorhodospira sibirica strain ATCC 700588
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