STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGZ46655.1Regulatory protein ArsR; KEGG: tgr:Tgr7_3286 putative transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR. (118 aa)    
Predicted Functional Partners:
EGZ46743.1
biotin/acetyl-CoA-carboxylase ligase; KEGG: tgr:Tgr7_2403 bifunctional protein BirA; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; Biotin protein ligase, C-terminal.
     
 0.736
EGZ46654.1
Rhodanese-like protein; KEGG: tgr:Tgr7_3285 rhodanese domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like.
  
  
 0.664
EGZ44815.1
Pyruvate dehydrogenase (NADP(+))., Pyruvate synthase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
     
 0.640
EGZ46656.1
PFAM: Peptidase M23; KEGG: tgr:Tgr7_3287 peptidase M23.
       0.614
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.604
EGZ50783.1
TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: tgr:Tgr7_2994 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase.
 
  
 0.597
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
  0.592
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
  0.589
EGZ46653.1
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
     
 0.549
EGZ43759.1
TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: alv:Alvin_1677 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase.
  
  
 0.544
Your Current Organism:
Thiorhodospira sibirica
NCBI taxonomy Id: 765914
Other names: T. sibirica ATCC 700588, Thiorhodospira sibirica A12, Thiorhodospira sibirica ATCC 700588, Thiorhodospira sibirica str. ATCC 700588, Thiorhodospira sibirica strain ATCC 700588
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.