STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
EGZ46139.1Lytic transglycosylase catalytic; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (705 aa)    
Predicted Functional Partners:
EGZ42749.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; PAS fold-4; Extracellular solute-binding protein, family 3; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: alv:Alvin_1490 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; Extracellular solute-bindi [...]
   
 0.935
EGZ49428.1
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
   
 0.920
EGZ46884.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; NMT1/THI5-like; Extracellular solute-binding protein, family 3; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; KEGG: hmo:HM1_1611 sensor histidine kinase, putative; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Extracellular solute-binding protein, family 3; PAS; PAC motif; Signal transduction response regulator [...]
   
 0.885
EGZ43527.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Extracellular solute-binding protein, family 3; PAS fold-4; PAS fold; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: alv:Alvin_2334 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Extracellular solute-binding prot [...]
   
 0.843
EGZ50714.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; HAMP linker domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: mgm:Mmc1_3164 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAC motif; PAS; Signal transduction response regulator, receiver domain.
   
 0.842
EGZ48182.1
KEGG: glo:Glov_2954 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain.
   
 0.842
EGZ45053.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold-4; PAS fold; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: dak:DaAHT2_0638 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif; Signal transduction response regulator, receiver domain.
   
 0.842
EGZ49604.1
Chorismate mutase; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; KEGG: tgr:Tgr7_1538 chorismate mutase; SMART: Chorismate mutase.
    
 0.839
EGZ42721.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; Signal transduction response regulator, receiver domain; Signal transduction hist [...]
    
 0.836
EGZ46885.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; KEGG: dsa:Desal_3800 PAS/PAC sensor signal transduction histidine kinase; SMART: Signal transduction response regulator, receiver domain; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain.
   
 0.834
Your Current Organism:
Thiorhodospira sibirica
NCBI taxonomy Id: 765914
Other names: T. sibirica ATCC 700588, Thiorhodospira sibirica A12, Thiorhodospira sibirica ATCC 700588, Thiorhodospira sibirica str. ATCC 700588, Thiorhodospira sibirica strain ATCC 700588
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