STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGZ43285.1KEGG: tkm:TK90_2268 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core. (458 aa)    
Predicted Functional Partners:
EGZ49428.1
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 0.988
EGZ42749.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; PAS fold-4; Extracellular solute-binding protein, family 3; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: alv:Alvin_1490 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; Extracellular solute-bindi [...]
  
 0.971
EGZ43286.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: tgr:Tgr7_0199 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 0.965
EGZ43527.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Extracellular solute-binding protein, family 3; PAS fold-4; PAS fold; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: alv:Alvin_2334 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Extracellular solute-binding prot [...]
  
 0.951
EGZ50688.1
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: tgr:Tgr7_1337 cobyrinic acid ac-diamide synthase.
  
 0.946
EGZ42721.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; Signal transduction response regulator, receiver domain; Signal transduction hist [...]
  
 0.945
EGZ46539.1
TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; KEGG: tgr:Tgr7_3261 signal transduction histidine kinase, nitrogen specific, NtrB; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.
 0.939
EGZ46884.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; NMT1/THI5-like; Extracellular solute-binding protein, family 3; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; KEGG: hmo:HM1_1611 sensor histidine kinase, putative; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Extracellular solute-binding protein, family 3; PAS; PAC motif; Signal transduction response regulator [...]
  
 0.931
EGZ50709.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; PAS fold-3; PAS fold-4; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif; Signal transduction response regulator, receiver domain.
  
 0.926
EGZ49631.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; HAMP linker domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAC motif; HAMP linker domain; PAS; Signal transduction response regulat [...]
  
 0.926
Your Current Organism:
Thiorhodospira sibirica
NCBI taxonomy Id: 765914
Other names: T. sibirica ATCC 700588, Thiorhodospira sibirica A12, Thiorhodospira sibirica ATCC 700588, Thiorhodospira sibirica str. ATCC 700588, Thiorhodospira sibirica strain ATCC 700588
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