Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PUV_02090Putative uncharacterized protein. (260 aa)    
Predicted Functional Partners:
msrAB
Peptide methionine sulfoxide reductase msrB/msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
    
   0.535
groS-A
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
       0.475
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
   0.424
groEL-A
Heat shock protein 60; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
       0.416
rpLL
50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
   
   0.413
rpmA
50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
    
   0.405
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
    
   0.405
rpsI
30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
    
   0.405
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
    
   0.405
rpmG
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.405
Your Current Organism:
Parachlamydia acanthamoebae
NCBI taxonomy Id: 765952
Other names: P. acanthamoebae UV-7, Parachlamydia acanthamoebae UV-7, Parachlamydia acanthamoebae str. UV-7, Parachlamydia acanthamoebae strain UV-7, Parachlamydia sp. UV-7
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