Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
queD-A6-carboxy-5,6,7,8-tetrahydropterin synthase. (125 aa)    
Predicted Functional Partners:
queE
7-carboxy-7-deazaguanine synthase homolog; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.983
folE-A
GTP cyclohydrolase 1.
  
 
 0.982
folE-B
GTP cyclohydrolase 1.
  
 
 0.931
queD-B
6-carboxy-5,6,7,8-tetrahydropterin synthase.
  
  
 
0.901
PUV_25150
Putative uncharacterized protein.
     
  0.900
queF
NADPH-dependent 7-cyano-7-deazaguanine reductase.
  
  
 0.775
queC-A
7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.757
queC-B
7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.749
PUV_02480
Putative uncharacterized protein.
       0.571
PUV_02490
Putative uncharacterized protein.
       0.425
Your Current Organism:
Parachlamydia acanthamoebae
NCBI taxonomy Id: 765952
Other names: P. acanthamoebae UV-7, Parachlamydia acanthamoebae UV-7, Parachlamydia acanthamoebae str. UV-7, Parachlamydia acanthamoebae strain UV-7, Parachlamydia sp. UV-7
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