Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
IDEInsulin-degrading enzyme; Belongs to the peptidase M16 family. (979 aa)    
Predicted Functional Partners:
PUV_02490
Putative uncharacterized protein.
       0.618
murC/ddl
Bifunctional enzyme MurC/Ddl; Cell wall formation; Belongs to the MurCDEF family.
    
   0.572
PUV_11560
Putative uncharacterized protein.
  
     0.550
cysJ
Sulfite reductase [NADPH] flavoprotein alpha-component.
  
 
  0.540
PUV_06710
Putative uncharacterized protein.
  
     0.509
PUV_06730
Putative uncharacterized protein.
  
     0.486
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 
 0.481
katA
Catalase.
     
  0.480
PUV_02480
Putative uncharacterized protein.
       0.456
petC
Cytochrome b6-f complex iron-sulfur subunit.
  
     0.444
Your Current Organism:
Parachlamydia acanthamoebae
NCBI taxonomy Id: 765952
Other names: P. acanthamoebae UV-7, Parachlamydia acanthamoebae UV-7, Parachlamydia acanthamoebae str. UV-7, Parachlamydia acanthamoebae strain UV-7, Parachlamydia sp. UV-7
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