Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aldAlanine dehydrogenase. (370 aa)    
Predicted Functional Partners:
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
 
 0.949
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.861
PUV_11850
Putative uncharacterized protein; Belongs to the TPP enzyme family.
     
 0.817
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.806
PUV_12190
Putative uncharacterized protein.
     
 0.806
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
  0.800
bkdB-B
2-oxoisovalerate dehydrogenase subunit beta,mitochondrial.
     
  0.800
bkdA
2-oxoisovalerate dehydrogenase subunit alpha,mitochondrial.
     
  0.800
pdhB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
  0.800
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
  0.800
Your Current Organism:
Parachlamydia acanthamoebae
NCBI taxonomy Id: 765952
Other names: P. acanthamoebae UV-7, Parachlamydia acanthamoebae UV-7, Parachlamydia acanthamoebae str. UV-7, Parachlamydia acanthamoebae strain UV-7, Parachlamydia sp. UV-7
Server load: medium (42%) [HD]