Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrABPeptide methionine sulfoxide reductase msrB/msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (284 aa)    
Predicted Functional Partners:
traF
Conjugal transfer disulfide-bond formation protein TraF.
   
 0.965
PUV_27380
Putative uncharacterized protein.
   
 
 0.962
PUV_11050
Putative uncharacterized protein.
       0.773
katA
Catalase.
   
 
 0.750
PUV_06970
Putative uncharacterized protein.
 
  
 0.728
PUV_11030
Putative uncharacterized protein.
  
    0.726
rpmJ
50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
    
 
 0.691
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.657
rpmG
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
   
 
 0.654
rpsP
30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
   0.645
Your Current Organism:
Parachlamydia acanthamoebae
NCBI taxonomy Id: 765952
Other names: P. acanthamoebae UV-7, Parachlamydia acanthamoebae UV-7, Parachlamydia acanthamoebae str. UV-7, Parachlamydia acanthamoebae strain UV-7, Parachlamydia sp. UV-7
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