node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A150USL9 | A0A150UWY1 | A0A150USL9 | A0A150UWY1 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | Protein kinase domain-containing protein. | 0.997 |
A0A150USL9 | A0A150V570 | A0A150USL9 | A0A150V570 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | YrdC-like domain-containing protein. | 0.525 |
A0A150USL9 | A0A150VCH7 | A0A150USL9 | A0A150VCH7 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.975 |
A0A150USL9 | KAE1 | A0A150USL9 | A0A150VC60 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.996 |
A0A150UWY1 | A0A150USL9 | A0A150UWY1 | A0A150USL9 | Protein kinase domain-containing protein. | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | 0.997 |
A0A150UWY1 | A0A150V570 | A0A150UWY1 | A0A150V570 | Protein kinase domain-containing protein. | YrdC-like domain-containing protein. | 0.529 |
A0A150UWY1 | A0A150V7U4 | A0A150UWY1 | A0A150V7U4 | Protein kinase domain-containing protein. | Uncharacterized protein. | 0.630 |
A0A150UWY1 | A0A150VCH7 | A0A150UWY1 | A0A150VCH7 | Protein kinase domain-containing protein. | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.974 |
A0A150UWY1 | A0A150VEE0 | A0A150UWY1 | A0A150VEE0 | Protein kinase domain-containing protein. | Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. | 0.509 |
A0A150UWY1 | A0A150VHJ2 | A0A150UWY1 | A0A150VHJ2 | Protein kinase domain-containing protein. | WD_REPEATS_REGION domain-containing protein. | 0.583 |
A0A150UWY1 | KAE1 | A0A150UWY1 | A0A150VC60 | Protein kinase domain-containing protein. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.996 |
A0A150UWY1 | TRM8 | A0A150UWY1 | A0A150VEG3 | Protein kinase domain-containing protein. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.644 |
A0A150UWY1 | TRM82 | A0A150UWY1 | A0A150URQ5 | Protein kinase domain-containing protein. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.541 |
A0A150UWY1 | TSR3 | A0A150UWY1 | A0A150VIP4 | Protein kinase domain-containing protein. | Ribosome biogenesis protein TSR3; Ribosome biogenesis protein required for processing 35S pre- rRNA at site D; Belongs to the TSR3 family. | 0.830 |
A0A150V570 | A0A150USL9 | A0A150V570 | A0A150USL9 | YrdC-like domain-containing protein. | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | 0.525 |
A0A150V570 | A0A150UWY1 | A0A150V570 | A0A150UWY1 | YrdC-like domain-containing protein. | Protein kinase domain-containing protein. | 0.529 |
A0A150V570 | A0A150VCH7 | A0A150V570 | A0A150VCH7 | YrdC-like domain-containing protein. | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.889 |
A0A150V570 | KAE1 | A0A150V570 | A0A150VC60 | YrdC-like domain-containing protein. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.889 |
A0A150V570 | TRM8 | A0A150V570 | A0A150VEG3 | YrdC-like domain-containing protein. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.554 |
A0A150V570 | TRM82 | A0A150V570 | A0A150URQ5 | YrdC-like domain-containing protein. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.534 |