STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A150UZ68Exonuclease domain-containing protein. (193 aa)    
Predicted Functional Partners:
M433DRAFT_4477
Uncharacterized protein; Belongs to the phosphohexose mutase family.
    
 0.918
M433DRAFT_6949
Exonuclease domain-containing protein.
   
 0.917
A0A150UWY5
Exonuclease domain-containing protein.
   
 0.902
A0A150VB65
Exonuclease domain-containing protein.
   
 0.789
A0A150UX03
Uncharacterized protein; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.
   
 0.694
PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]
   
 0.668
A0A150V1G3
Uncharacterized protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.592
A0A150UQS0
Uncharacterized protein.
      
 0.526
A0A150VI60
Lactamase_B_4 domain-containing protein.
      
 0.526
A0A150UTY0
Uncharacterized protein.
      
 0.455
Your Current Organism:
Acidomyces richmondensis
NCBI taxonomy Id: 766039
Other names: A. richmondensis BFW, Acidomyces richmondensis BFW
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.