A0A150V245 protein (Acidomyces richmondensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A150V245

Peptidase_S9 domain-containing protein. (899 aa)

Predicted Functional Partners:

M433DRAFT_5355

0.759

A0A150VDN9

0.625

A0A150V0K8

0.460

A0A150V6H8

0.459

A0A150V664

0.441

A0A150URJ3

0.435

A0A150V6I6

0.435

M433DRAFT_720

0.435

M433DRAFT_718

0.435

A0A150VHC6

0.435

Your Current Organism:

Acidomyces richmondensis

NCBI taxonomy Id: 766039
Other names: A. richmondensis BFW, Acidomyces richmondensis BFW

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A150URJ3	A0A150V245	A0A150URJ3	A0A150V245	HMA domain-containing protein.	Peptidase_S9 domain-containing protein.	0.435
A0A150V0K8	A0A150V245	A0A150V0K8	A0A150V245	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Peptidase_S9 domain-containing protein.	0.460
A0A150V245	A0A150URJ3	A0A150V245	A0A150URJ3	Peptidase_S9 domain-containing protein.	HMA domain-containing protein.	0.435
A0A150V245	A0A150V0K8	A0A150V245	A0A150V0K8	Peptidase_S9 domain-containing protein.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.460
A0A150V245	A0A150V664	A0A150V245	A0A150V664	Peptidase_S9 domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.441
A0A150V245	A0A150V6H8	A0A150V245	A0A150V6H8	Peptidase_S9 domain-containing protein.	Pex2_Pex12 domain-containing protein.	0.459
A0A150V245	A0A150V6I6	A0A150V245	A0A150V6I6	Peptidase_S9 domain-containing protein.	Uncharacterized protein.	0.435
A0A150V245	A0A150VDN9	A0A150V245	A0A150VDN9	Peptidase_S9 domain-containing protein.	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	0.625
A0A150V245	A0A150VHC6	A0A150V245	A0A150VHC6	Peptidase_S9 domain-containing protein.	Uncharacterized protein.	0.435
A0A150V245	M433DRAFT_5355	A0A150V245	A0A150V1X4	Peptidase_S9 domain-containing protein.	PUM-HD domain-containing protein.	0.759
A0A150V245	M433DRAFT_718	A0A150V245	A0A150VHC5	Peptidase_S9 domain-containing protein.	Uncharacterized protein.	0.435
A0A150V245	M433DRAFT_720	A0A150V245	A0A150VHA1	Peptidase_S9 domain-containing protein.	Uncharacterized protein.	0.435
A0A150V664	A0A150V245	A0A150V664	A0A150V245	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Peptidase_S9 domain-containing protein.	0.441
A0A150V6H8	A0A150V245	A0A150V6H8	A0A150V245	Pex2_Pex12 domain-containing protein.	Peptidase_S9 domain-containing protein.	0.459
A0A150V6I6	A0A150V245	A0A150V6I6	A0A150V245	Uncharacterized protein.	Peptidase_S9 domain-containing protein.	0.435
A0A150VDN9	A0A150V245	A0A150VDN9	A0A150V245	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.	Peptidase_S9 domain-containing protein.	0.625
A0A150VHC6	A0A150V245	A0A150VHC6	A0A150V245	Uncharacterized protein.	Peptidase_S9 domain-containing protein.	0.435
M433DRAFT_5355	A0A150V245	A0A150V1X4	A0A150V245	PUM-HD domain-containing protein.	Peptidase_S9 domain-containing protein.	0.759
M433DRAFT_718	A0A150V245	A0A150VHC5	A0A150V245	Uncharacterized protein.	Peptidase_S9 domain-containing protein.	0.435
M433DRAFT_720	A0A150V245	A0A150VHA1	A0A150V245	Uncharacterized protein.	Peptidase_S9 domain-containing protein.	0.435

Network Stats

number of nodes:

11

number of edges:

34

average node degree:

6.18

avg. local clustering coefficient:

0.958

expected number of edges:

16

PPI enrichment p-value:

7.21e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042254

Ribosome biogenesis

8 of 258

1.27

1.58

2.60e-06

GO:0016072

rRNA metabolic process

7 of 202

1.32

1.58

8.07e-06

GO:0006364

rRNA processing

6 of 190

1.28

1.3

0.00014

GO:0000463

Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

3 of 23

1.9

1.3

0.0026

GO:0042273

Ribosomal large subunit biogenesis

4 of 71

1.53

1.23

0.0016

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005730

Nucleolus

7 of 218

1.29

1.52

9.72e-06

GO:0030687

Preribosome, large subunit precursor

3 of 32

1.76

1.26

0.0026

GO:0043232

Intracellular non-membrane-bounded organelle

8 of 871

0.75

0.58

0.0020

GO:0005634

Nucleus

10 of 1664

0.56

0.44

0.0020

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2035

Mixed, incl. UBX domain, and VCP-NPL4-UFD1 AAA ATPase complex

4 of 13

2.27

2.92

1.75e-06

CL:3948

Preribosome, large subunit precursor, and Ribosomal large subunit biogenesis

5 of 55

1.74

2.35

2.46e-06

CL:3946

Preribosome, and Nucleolus

6 of 108

1.53

2.06

1.75e-06

CL:3952

Preribosome, large subunit precursor, and Ribosomal large subunit biogenesis

4 of 41

1.77

1.95

4.61e-05

CL:3937

rRNA processing, and mRNA decay by 3 to 5 exoribonuclease

7 of 156

1.44

1.91

1.54e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005730

Nucleolus

4 of 94

1.41

0.97

0.0058

GOCC:0005634

Nucleus

9 of 997

0.74

0.59

0.0014

GOCC:0043231

Intracellular membrane-bounded organelle

10 of 2125

0.46

0.32

0.0248

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00166

Domain present in ubiquitin-regulatory proteins

2 of 3

2.61

1.19

0.0067

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Credits

Access

Info

About

STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About