A0A150VA89 protein (Acidomyces richmondensis)

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second shell of interactors

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Known Interactions

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Predicted Interactions

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gene fusions

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protein homology

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Score

A0A150VA89

Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (398 aa)

Predicted Functional Partners:

A0A150VEC2

0.691

A0A150VAA5

0.641

A0A150VFT8

0.617

A0A150VGE5

0.610

A0A150VGL0

0.610

A0A150UV51

0.574

M433DRAFT_6967

0.572

A0A150V2V7

0.557

A0A150V0D1

0.528

A0A150VE11

0.520

Your Current Organism:

Acidomyces richmondensis

NCBI taxonomy Id: 766039
Other names: A. richmondensis BFW, Acidomyces richmondensis BFW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A150UV51	A0A150VA89	A0A150UV51	A0A150VA89	P/Homo B domain-containing protein; Belongs to the peptidase S8 family.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.574
A0A150UV51	A0A150VEC2	A0A150UV51	A0A150VEC2	P/Homo B domain-containing protein; Belongs to the peptidase S8 family.	Uncharacterized protein; Belongs to the peptidase S8 family.	0.520
A0A150UV51	M433DRAFT_6967	A0A150UV51	A0A150UWH5	P/Homo B domain-containing protein; Belongs to the peptidase S8 family.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.570
A0A150V0D1	A0A150VA89	A0A150V0D1	A0A150VA89	Carbohydrate-binding module family 48 protein.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.528
A0A150V2V7	A0A150VA89	A0A150V2V7	A0A150VA89	Uncharacterized protein.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.557
A0A150V2V7	A0A150VAA5	A0A150V2V7	A0A150VAA5	Uncharacterized protein.	Glycosyltransferase family 1 protein.	0.410
A0A150VA89	A0A150UV51	A0A150VA89	A0A150UV51	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	P/Homo B domain-containing protein; Belongs to the peptidase S8 family.	0.574
A0A150VA89	A0A150V0D1	A0A150VA89	A0A150V0D1	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Carbohydrate-binding module family 48 protein.	0.528
A0A150VA89	A0A150V2V7	A0A150VA89	A0A150V2V7	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Uncharacterized protein.	0.557
A0A150VA89	A0A150VAA5	A0A150VA89	A0A150VAA5	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Glycosyltransferase family 1 protein.	0.641
A0A150VA89	A0A150VE11	A0A150VA89	A0A150VE11	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Phosphotransferase.	0.520
A0A150VA89	A0A150VEC2	A0A150VA89	A0A150VEC2	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Uncharacterized protein; Belongs to the peptidase S8 family.	0.691
A0A150VA89	A0A150VFT8	A0A150VA89	A0A150VFT8	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Reticulon-like protein.	0.617
A0A150VA89	A0A150VGE5	A0A150VA89	A0A150VGE5	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.610
A0A150VA89	A0A150VGL0	A0A150VA89	A0A150VGL0	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Uncharacterized protein.	0.610
A0A150VA89	M433DRAFT_6967	A0A150VA89	A0A150UWH5	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.572
A0A150VAA5	A0A150V2V7	A0A150VAA5	A0A150V2V7	Glycosyltransferase family 1 protein.	Uncharacterized protein.	0.410
A0A150VAA5	A0A150VA89	A0A150VAA5	A0A150VA89	Glycosyltransferase family 1 protein.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.641
A0A150VE11	A0A150VA89	A0A150VE11	A0A150VA89	Phosphotransferase.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.520
A0A150VEC2	A0A150UV51	A0A150VEC2	A0A150UV51	Uncharacterized protein; Belongs to the peptidase S8 family.	P/Homo B domain-containing protein; Belongs to the peptidase S8 family.	0.520

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Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.968

expected number of edges:

16

PPI enrichment p-value:

1.33e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042273

Ribosomal large subunit biogenesis

10 of 77

1.98

5.59

4.57e-16

GO:0000470

Maturation of LSU-rRNA

7 of 41

2.09

4.54

4.47e-11

GO:0000463

Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

6 of 30

2.16

4.16

1.09e-09

GO:0042254

Ribosome biogenesis

11 of 274

1.47

2.94

1.49e-13

GO:0006364

rRNA processing

9 of 204

1.51

2.73

1.85e-10

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043021

Ribonucleoprotein complex binding

3 of 41

1.73

0.75

0.0338

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030687

Preribosome, large subunit precursor

9 of 35

2.27

7.01

7.92e-17

GO:0005730

Nucleolus

11 of 215

1.57

3.56

2.69e-15

GO:0005654

Nucleoplasm

4 of 211

1.14

0.77

0.0085

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4695

Preribosome, large subunit precursor, and Ribosomal large subunit export from nucleus

10 of 28

2.42

8.78

2.32e-20

CL:4698

Preribosome, large subunit precursor, and ATPase binding

9 of 21

2.49

8.61

4.01e-19

CL:4684

Preribosome, large subunit precursor, and DEAD/DEAH box helicase domain

11 of 63

2.1

7.28

2.32e-20

CL:4723

Mixed, incl. Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, and ATPase binding

3 of 6

2.56

2.59

1.45e-05

CL:4700

Maturation of LSU-rRNA, and PUA domain

3 of 10

2.34

2.27

4.62e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6791226

Major pathway of rRNA processing in the nucleolus and cytosol

6 of 134

1.51

1.86

9.99e-06

MAP-8868773

rRNA processing in the nucleus and cytosol

6 of 138

1.5

1.84

9.99e-06

MAP-72312

rRNA processing

6 of 141

1.49

1.83

9.99e-06

MAP-8953854

Metabolism of RNA

7 of 553

0.96

0.85

0.00046

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030687

Preribosome, large subunit precursor

3 of 22

2.0

1.6

0.00067

GOCC:0031981

Nuclear lumen

8 of 457

1.11

1.2

1.58e-05

GOCC:0005730

Nucleolus

3 of 98

1.35

0.67

0.0345

GOCC:0005634

Nucleus

9 of 1134

0.76

0.66

0.00023

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0690

Ribosome biogenesis

4 of 18

2.21

2.77

3.05e-06

KW-0698

rRNA processing

3 of 17

2.11

1.85

0.00024

KW-0539

Nucleus

5 of 273

1.13

0.94

0.0014

KW-0489

Methyltransferase

2 of 30

1.69

0.69

0.0458

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR030378

Circularly permuted (CP)-type guanine nucleotide-binding (G) domain

2 of 2

2.86

0.89

0.0247

IPR023179

GTP-binding protein, orthogonal bundle domain superfamily

2 of 3

2.69

0.89

0.0247

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