STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M433DRAFT_1914ERCC4 domain-containing protein. (943 aa)    
Predicted Functional Partners:
A0A150V9U9
Uncharacterized protein.
   
 0.999
A0A150VCA9
3'-5' exonuclease domain-containing protein.
    
 0.997
A0A150VHT5
DUF1767 domain-containing protein.
    
 0.988
A0A150V175
XPA_C domain-containing protein.
    
 0.984
A0A150VH39
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.983
A0A150VH90
AA_TRNA_LIGASE_II domain-containing protein.
   
 0.981
A0A150VA37
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.969
M433DRAFT_5508
MPN domain-containing protein.
   
 0.968
A0A150VE49
Uncharacterized protein.
    
 0.968
A0A150UX18
Uncharacterized protein.
   
 0.959
Your Current Organism:
Acidomyces richmondensis
NCBI taxonomy Id: 766039
Other names: A. richmondensis BFW, Acidomyces richmondensis BFW
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.