A0A150VJM7 protein (Acidomyces richmondensis)

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Known Interactions

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experimentally determined

Predicted Interactions

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A0A150VJM7

Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (159 aa)

Predicted Functional Partners:

A0A150VFT0

0.980

M433DRAFT_67

0.772

M433DRAFT_1948

0.720

A0A150V689

0.491

A0A150V6Q0

0.491

A0A150VJ14

0.408

Your Current Organism:

Acidomyces richmondensis

NCBI taxonomy Id: 766039
Other names: A. richmondensis BFW, Acidomyces richmondensis BFW

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A150V689	A0A150VJM7	A0A150V689	A0A150VJM7	Uncharacterized protein.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.491
A0A150V689	M433DRAFT_67	A0A150V689	A0A150VK39	Uncharacterized protein.	Sm domain-containing protein.	0.930
A0A150V6Q0	A0A150VJM7	A0A150V6Q0	A0A150VJM7	Uncharacterized protein.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.491
A0A150V6Q0	M433DRAFT_1948	A0A150V6Q0	A0A150VDE7	Uncharacterized protein.	Sm domain-containing protein.	0.899
A0A150V6Q0	M433DRAFT_67	A0A150V6Q0	A0A150VK39	Uncharacterized protein.	Sm domain-containing protein.	0.930
A0A150VFT0	A0A150VJM7	A0A150VFT0	A0A150VJM7	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.980
A0A150VJ14	A0A150VJM7	A0A150VJ14	A0A150VJM7	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.408
A0A150VJM7	A0A150V689	A0A150VJM7	A0A150V689	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Uncharacterized protein.	0.491
A0A150VJM7	A0A150V6Q0	A0A150VJM7	A0A150V6Q0	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Uncharacterized protein.	0.491
A0A150VJM7	A0A150VFT0	A0A150VJM7	A0A150VFT0	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.980
A0A150VJM7	A0A150VJ14	A0A150VJM7	A0A150VJ14	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.408
A0A150VJM7	M433DRAFT_1948	A0A150VJM7	A0A150VDE7	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Sm domain-containing protein.	0.720
A0A150VJM7	M433DRAFT_67	A0A150VJM7	A0A150VK39	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Sm domain-containing protein.	0.772
M433DRAFT_1948	A0A150V6Q0	A0A150VDE7	A0A150V6Q0	Sm domain-containing protein.	Uncharacterized protein.	0.899
M433DRAFT_1948	A0A150VJM7	A0A150VDE7	A0A150VJM7	Sm domain-containing protein.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.720
M433DRAFT_1948	M433DRAFT_67	A0A150VDE7	A0A150VK39	Sm domain-containing protein.	Sm domain-containing protein.	0.998
M433DRAFT_67	A0A150V689	A0A150VK39	A0A150V689	Sm domain-containing protein.	Uncharacterized protein.	0.930
M433DRAFT_67	A0A150V6Q0	A0A150VK39	A0A150V6Q0	Sm domain-containing protein.	Uncharacterized protein.	0.930
M433DRAFT_67	A0A150VJM7	A0A150VK39	A0A150VJM7	Sm domain-containing protein.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.772
M433DRAFT_67	M433DRAFT_1948	A0A150VK39	A0A150VDE7	Sm domain-containing protein.	Sm domain-containing protein.	0.998

Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.868

expected number of edges:

15

PPI enrichment p-value:

6.42e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051537

2 iron, 2 sulfur cluster binding

4 of 22

1.67

1.47

0.00058

GO:0051536

Iron-sulfur cluster binding

5 of 72

1.25

1.06

0.0012

GO:0016491

Oxidoreductase activity

9 of 356

0.81

0.72

0.00025

GO:0046872

Metal ion binding

7 of 425

0.63

0.37

0.0448

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1516

Mixed, incl. Rieske [2Fe-2S] domain, and Nitrotoluene catabolic process

5 of 7

2.27

3.39

1.55e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01120

Microbial metabolism in diverse environments

7 of 253

0.85

0.69

0.0015

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0001

2Fe-2S

2 of 6

1.93

0.77

0.0350

KW-0186

Copper

2 of 7

1.87

0.76

0.0350

KW-0411

Iron-sulfur

3 of 35

1.34

0.67

0.0350

KW-0408

Iron

4 of 77

1.13

0.6

0.0350

KW-0560

Oxidoreductase

4 of 124

0.92

0.5

0.0408

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036010

2Fe-2S ferredoxin-like superfamily

3 of 9

1.93

1.01

0.0113

IPR001041

2Fe-2S ferredoxin-type iron-sulfur binding domain

3 of 9

1.93

1.01

0.0113

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