STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DVR1Protein DVR-1 homolog; Belongs to the TGF-beta family. (461 aa)    
Predicted Functional Partners:
W4XNK0_STRPU
Uncharacterized protein.
    
 0.962
W4Y7K5_STRPU
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.957
W4YVX7_STRPU
CTCK domain-containing protein.
    
  0.903
W4Z9E4_STRPU
Uncharacterized protein.
   
 
  0.900
W4Z063_STRPU
TGF_BETA_2 domain-containing protein.
  
0.747
BMP2/4
TGF_BETA_2 domain-containing protein.
  
0.746
W4XBR5_STRPU
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.691
W4Z7H3_STRPU
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.691
W4ZA17_STRPU
Uncharacterized protein.
    
 0.664
W4YJP4_STRPU
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
    
 0.607
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.