STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2AHistone H2A, embryonic; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa)    
Predicted Functional Partners:
W4XJG9_STRPU
Uncharacterized protein.
    
 0.793
W4Y7F6_STRPU
Uncharacterized protein.
    
 0.793
W4YCR4_STRPU
Uncharacterized protein.
    
 0.793
H3I1F0_STRPU
Histone H3; Belongs to the histone H3 family.
 
 
 0.735
H3IYA6_STRPU
Histone H3; Belongs to the histone H3 family.
 
 
 0.735
H3_STRPU
Histone H3, embryonic; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.735
W4XAB3_STRPU
Histone H3; Belongs to the histone H3 family.
 
 
 0.735
W4XCB6_STRPU
Histone H3; Belongs to the histone H3 family.
   
 0.735
W4XJN4_STRPU
Histone H3; Belongs to the histone H3 family.
 
 
 0.735
W4XKA2_STRPU
Histone H3; Belongs to the histone H3 family.
 
 
 0.735
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.