STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4XI29_STRPUC3H1-type domain-containing protein. (859 aa)    
Predicted Functional Partners:
W4XKM1_STRPU
Fip1 domain-containing protein.
    
 0.970
W4ZEA4_STRPU
Uncharacterized protein.
   
 0.970
W4XRY7_STRPU
Uncharacterized protein.
   
 0.967
W4Z078_STRPU
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
    
 0.967
W4ZD81_STRPU
Uncharacterized protein.
   
 0.963
W4YPV2_STRPU
RRM domain-containing protein.
   
 0.949
W4XZG8_STRPU
WD_REPEATS_REGION domain-containing protein.
   
 
 0.927
W4Y5T6_STRPU
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.917
W4Y8J2_STRPU
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.917
W4YGE7_STRPU
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
    
 0.910
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.