STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gpc-6Uncharacterized protein; Belongs to the glypican family. (626 aa)    
Predicted Functional Partners:
Sdc
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.914
W4YQM2_STRPU
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
     
 0.868
W4Y7Q6_STRPU
Sulfotransfer_1 domain-containing protein.
     
 0.852
W4Y4I5_STRPU
Uncharacterized protein.
     
 0.815
W4Y723_STRPU
Uncharacterized protein.
    
 0.804
W4YII5_STRPU
Uncharacterized protein.
    
 0.804
W4XHS8_STRPU
HH_signal domain-containing protein.
    
 0.796
Hh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.796
W4YFX3_STRPU
Uncharacterized protein.
    
 0.782
Gpc-5
Uncharacterized protein; Belongs to the glypican family.
  
 
0.770
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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