STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4XXM0_STRPUCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa)    
Predicted Functional Partners:
W4YU96_STRPU
F-box domain-containing protein.
   
 0.975
W4Z8N3_STRPU
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.952
CycA
Uncharacterized protein; Belongs to the cyclin family.
   
 0.917
W4Y643_STRPU
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.917
W4XHR1_STRPU
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.870
Q964G0_STRPU
Cyclin D; Belongs to the cyclin family.
   
 0.848
W4XQK4_STRPU
Uncharacterized protein.
   
 0.823
W4XSP6_STRPU
Uncharacterized protein; Belongs to the cyclin family.
   
 0.823
W4YHN9_STRPU
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.823
W4ZEI2_STRPU
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.823
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.