STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4XYH0_STRPUE3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (196 aa)    
Predicted Functional Partners:
W4XBJ4_STRPU
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
   0.723
W4YD19_STRPU
Uncharacterized protein.
    
 
 0.657
W4YD20_STRPU
SGS domain-containing protein.
    
 
 0.657
W4XG47_STRPU
Ubiquitinyl hydrolase 1.
    
 0.544
W4YUF3_STRPU
Uncharacterized protein.
    
 0.544
W4XUQ0_STRPU
Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
 
 0.458
W4ZFU0_STRPU
Gp_dh_C domain-containing protein.
   
 
 0.458
W4YF95_STRPU
Tyrosine--tRNA ligase.
      
 0.400
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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