STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4Y374_STRPUFe2OG dioxygenase domain-containing protein. (239 aa)    
Predicted Functional Partners:
W4XQK1_STRPU
2OG-FeII_Oxy_2 domain-containing protein.
   
  
 0.661
W4YGS9_STRPU
Uncharacterized protein.
    
 
 0.644
W4ZJB8_STRPU
Uncharacterized protein.
    
 
 0.644
W4XBB7_STRPU
Uncharacterized protein.
      
 0.586
W4XPC9_STRPU
Uncharacterized protein.
      
 0.580
W4YEX0_STRPU
2OG-FeII_Oxy_2 domain-containing protein.
   
  
 0.576
W4YIA3_STRPU
Fe2OG dioxygenase domain-containing protein.
      
 0.538
W4YIY6_STRPU
Uncharacterized protein.
      
 0.448
MED6
Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 
 0.419
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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