STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4Z0B1_STRPUUncharacterized protein; Belongs to the actin family. (378 aa)    
Predicted Functional Partners:
W4XKN3_STRPU
DH domain-containing protein.
     
 0.728
W4XJG9_STRPU
Uncharacterized protein.
   
 0.696
W4Y7F6_STRPU
Uncharacterized protein.
   
 0.696
W4YCR4_STRPU
Uncharacterized protein.
   
 0.696
W4X9T4_STRPU
Uncharacterized protein.
   
 0.667
W4YRR7_STRPU
Uncharacterized protein.
   
 0.637
W4XXF3_STRPU
RuvB-like helicase; Belongs to the RuvB family.
   
 0.631
W4YSD0_STRPU
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
  
0.630
W4YNX5_STRPU
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.629
W4Y916_STRPU
Uncharacterized protein.
   
 0.626
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.