STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4Z2I4_STRPUTranscription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (103 aa)    
Predicted Functional Partners:
W4Y881_STRPU
Ubiquitin carboxyl-terminal hydrolase.
    
 0.981
W4YUW4_STRPU
SCA7 domain-containing protein.
    
 0.981
W4ZIN9_STRPU
SGF29 C-terminal domain-containing protein.
   
 0.974
W4XAZ3_STRPU
Uncharacterized protein.
   
 
 0.966
W4XS74_STRPU
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
   
 0.964
W4XD53_STRPU
TFIID_20kDa domain-containing protein.
   
 0.960
W4Y7I9_STRPU
RRM domain-containing protein.
    
 
 0.955
W4Z1D6_STRPU
Uncharacterized protein.
   
 0.953
W4XPI4_STRPU
Uncharacterized protein.
    
 0.942
W4XJD3_STRPU
Uncharacterized protein.
    
 0.933
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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