STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4Z5M8_STRPUL27 domain-containing protein. (182 aa)    
Predicted Functional Partners:
W4ZL26_STRPU
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.685
W4XS65_STRPU
Pribosyltran domain-containing protein.
  
 
 0.644
W4Y230_STRPU
Vang-like protein.
    
 0.633
W4Z502_STRPU
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]
    
 0.628
W4XSY8_STRPU
Uncharacterized protein.
   
 
 0.624
W4Z8Z7_STRPU
RabBD domain-containing protein.
   
 
 0.624
W4YW35_STRPU
RabBD domain-containing protein.
   
 
 0.622
W4XYA4_STRPU
PID domain-containing protein.
    
 0.601
W4XYA5_STRPU
Uncharacterized protein.
    
 0.601
W4ZFW0_STRPU
Uncharacterized protein.
    
 0.601
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.