STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W4Z713_STRPUUncharacterized protein. (986 aa)    
Predicted Functional Partners:
W4Z4M9_STRPU
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.951
eIF4E1
Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.
   
 0.948
W4YHR9_STRPU
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.923
eif4e3
Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family.
   
 0.824
W4XN61_STRPU
RRM domain-containing protein.
   
 0.783
W4Y2A5_STRPU
Nuclear cap-binding protein subunit 2.
    
 0.779
W4YGC3_STRPU
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.774
W4XY96_STRPU
RRM domain-containing protein.
   
 0.753
W4YSV9_STRPU
W2 domain-containing protein.
   
 0.749
W4YCB9_STRPU
Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
 0.732
Your Current Organism:
Strongylocentrotus purpuratus
NCBI taxonomy Id: 7668
Other names: S. purpuratus, purple sea urchin, purple urchin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.