STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiX_1Sirohydrochlorin cobaltochelatase. (408 aa)    
Predicted Functional Partners:
cobJ
precorrin-3B C(17)-methyltransferase.
   
 0.998
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
 0.996
cobA
uroporphyrinogen-III C-methyltransferase.
  
 0.994
cobM
Precorrin-4 C(11)-methyltransferase.
   
 0.982
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
   
 0.981
cobI
Precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
   
 0.979
cbiE
Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit.
     
 0.976
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.961
AFN46301.1
Porphobilinogen deaminase, dipyromethane cofactor-binding domain protein.
 
  
 0.961
cobH_1
precorrin-8X methylmutase.
    
 0.948
Your Current Organism:
Pseudopropionibacterium propionicum
NCBI taxonomy Id: 767029
Other names: P. propionicum F0230a, Propionibacterium propionicum F0230a, Pseudopropionibacterium propionicum F0230a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.