Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lpdA_1Dihydrolipoyl dehydrogenase. (455 aa)    
Predicted Functional Partners:
AFN46853.1
Dehydrogenase E1 component.
 
 0.999
sucA
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
  
 0.999
AFN46095.1
E3 binding domain protein.
 0.998
sucB
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase.
 0.995
AFN46846.1
E3 binding domain protein.
 0.989
pdhB
Pyruvate dehydrogenase E1 component subunit beta.
 
 0.981
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.967
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.964
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit.
 
 
 0.963
nifJ
Pyruvate synthase.
  
 
 0.955
Your Current Organism:
Pseudopropionibacterium propionicum
NCBI taxonomy Id: 767029
Other names: P. propionicum F0230a, Propionibacterium propionicum F0230a, Pseudopropionibacterium propionicum F0230a
Server load: medium (48%) [HD]