node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFN45022.1 | AFN45957.1 | HMPREF9154_0697 | HMPREF9154_0698 | Putative Zn-dependent protease. | TipAS antibiotic-recognition domain protein. | 0.924 |
AFN45022.1 | AFN46617.1 | HMPREF9154_0697 | HMPREF9154_0696 | Putative Zn-dependent protease. | ABC transporter transmembrane region. | 0.521 |
AFN45022.1 | AFN47208.1 | HMPREF9154_0697 | HMPREF9154_0699 | Putative Zn-dependent protease. | Putative ribose-5-phosphate isomerase B. | 0.617 |
AFN45022.1 | AFN47413.1 | HMPREF9154_0697 | HMPREF9154_0695 | Putative Zn-dependent protease. | ABC transporter, ATP-binding protein. | 0.521 |
AFN45957.1 | AFN45022.1 | HMPREF9154_0698 | HMPREF9154_0697 | TipAS antibiotic-recognition domain protein. | Putative Zn-dependent protease. | 0.924 |
AFN45957.1 | AFN46617.1 | HMPREF9154_0698 | HMPREF9154_0696 | TipAS antibiotic-recognition domain protein. | ABC transporter transmembrane region. | 0.533 |
AFN45957.1 | AFN47208.1 | HMPREF9154_0698 | HMPREF9154_0699 | TipAS antibiotic-recognition domain protein. | Putative ribose-5-phosphate isomerase B. | 0.618 |
AFN45957.1 | AFN47413.1 | HMPREF9154_0698 | HMPREF9154_0695 | TipAS antibiotic-recognition domain protein. | ABC transporter, ATP-binding protein. | 0.533 |
AFN45957.1 | dnaJ | HMPREF9154_0698 | HMPREF9154_2563 | TipAS antibiotic-recognition domain protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.507 |
AFN45957.1 | dnaJ-2 | HMPREF9154_0698 | HMPREF9154_1730 | TipAS antibiotic-recognition domain protein. | Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | 0.507 |
AFN45957.1 | glyA | HMPREF9154_0698 | HMPREF9154_0694 | TipAS antibiotic-recognition domain protein. | Putative glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.422 |
AFN45957.1 | rpoB | HMPREF9154_0698 | HMPREF9154_2293 | TipAS antibiotic-recognition domain protein. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.409 |
AFN46617.1 | AFN45022.1 | HMPREF9154_0696 | HMPREF9154_0697 | ABC transporter transmembrane region. | Putative Zn-dependent protease. | 0.521 |
AFN46617.1 | AFN45957.1 | HMPREF9154_0696 | HMPREF9154_0698 | ABC transporter transmembrane region. | TipAS antibiotic-recognition domain protein. | 0.533 |
AFN46617.1 | AFN47208.1 | HMPREF9154_0696 | HMPREF9154_0699 | ABC transporter transmembrane region. | Putative ribose-5-phosphate isomerase B. | 0.427 |
AFN46617.1 | AFN47413.1 | HMPREF9154_0696 | HMPREF9154_0695 | ABC transporter transmembrane region. | ABC transporter, ATP-binding protein. | 0.821 |
AFN46617.1 | glyA | HMPREF9154_0696 | HMPREF9154_0694 | ABC transporter transmembrane region. | Putative glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.538 |
AFN47208.1 | AFN45022.1 | HMPREF9154_0699 | HMPREF9154_0697 | Putative ribose-5-phosphate isomerase B. | Putative Zn-dependent protease. | 0.617 |
AFN47208.1 | AFN45957.1 | HMPREF9154_0699 | HMPREF9154_0698 | Putative ribose-5-phosphate isomerase B. | TipAS antibiotic-recognition domain protein. | 0.618 |
AFN47208.1 | AFN46617.1 | HMPREF9154_0699 | HMPREF9154_0696 | Putative ribose-5-phosphate isomerase B. | ABC transporter transmembrane region. | 0.427 |